Does any body know what would make an extruder extrude 10X the plastic?

Does any body know what would make an extruder extrude 10X the plastic?
I have configured a “clean” marlin firmware and still it is 10X to much. clicking the extrude 1mm button in repetier host does 10 and 10 does 100.
Please help.

my extrusion multiplier is at 1

E steps/mm being significantly out?

Simple test would be to measure how much filament is moved by e.g. extruding 1mm manually in pronterface.

That would eliminate slicer setting errors from firmware setting errors.

You might not be factoring in the correct micro-stepping value into your E steps/mm value?

I’d double check your EEPROM settings–what does an M501 result in for your e-steps?