If possible, I’d do 2 separate STLs, one for the letters, one for the rest. Print the non-letter part at high speed. Do not turn off bed heating. Slice the letter STL with the appropiate z-offset and speed. Slic3r can do z-offsets, but its auto-centering of objects may put things off. Anyway, you could, say, add a “register” by printing the coin brim AND letters in the letter stl, and a brim-less coin with brain, and therefore it’d be centered.
In Simplify3D, you can make processes that act on layer height regions. It would be simple to make one process for the lower layers, and another for the upper, with completely different print settings as you see fit.
Check out Slice3r Prusa Edition. It allows “Mods” which are solid areas imported into your model where you can modify the settings (including speed) in just that area. As a separate function, it also allows layer editing to control layer height in multiple Z areas as needed. For your example a “Mod” would probably just be an extents cube with its base at the Z height where your lettering starts. missing/deleted image from Google+
Here is a similar example to yours with the gcode out of Slic3r loaded into Matter Control which shows the speeds used in each area. As the color key shows, the top details are slower than the bottom. missing/deleted image from Google+
Hmm, It seems to work pretty good on entire Z levels, or details that are separated by an XY distance (like spires on a castle). If you just plunk a shape into the middle of a model though, it looks like you will get seams as if it were a separate area. The below pictures show this. (I don’t see why you would do what I’m showing, but it’s good to know the limitations.) missing/deleted image from Google+